Role of catecholamine in tumor angiogenesis linked to capacitance relaxation phenomenon

Abstract

The present paper describes the role of catecholamine with chromogranin A(CgA) in tumor angiogenesis linked 
to capacitance relaxation phenomenonl. The capacitance relaxation phenomenon is the observation about the 
capacitance value which jumps rapidly in cancer cell around 200Hz.It has been established that catecholamine 
is of recent interest in regulation of angiogenesis. The present paper deals with chromogranin A (CgA), 
coreleased with catecholamine in plasma in patients suffering from pheochromocytoma(PHEO), multiple 
endocrine neoplasia (MEN), medullary thyroid carcinoma (MTC), and congenital adrenal hyperplasia(CAH) and 
patients with others endocrine disorders. The paper also discusses the progressive rise in CgA with 
catecholamine linked to capacitance relaxation phenomenon. The experimental results of capacitance relaxation 
phenomenon were given as inputs to a model for correlation with the CgA level and catecholamine. It is to be 
noted that the model is simulated in MATLAB 7.0. MATLAB allows matrix manipulations, plotting of functions 
and data, implementation of algorithms, creation of user interface and interfacing with programs written in other 
languages.