Challenges in determining the order of nucleotides within a DNA molecule using the DNA technologies
Keywords:
DNA sequencing, molecules, behavior, characteristics, physical descriptions.Abstract
The advent of second and third generation DNA sequencing techniqnologies have revolutionized the
genomics research. The Single Molecule Sequencing technologies are adequate to minimize occurrence
of errors in sequencing. The third generation sequencing technologies could overcome limitations of
first and second-generation sequencing technologies. The almost complete human genome sequencing
was performed by using single molecular sequencing technologies. Benefits, risks and safeguards
associated with the disclosure of information of very intimate kind contained in human genome, were
also discussed. The power of whole sequencing for human welfare arises only from associations with
medical histories, behavioral characteristics, physical descriptions and genome-environment
interactions not from mere knowledge of base pairs.
