Screening for the presence of Helicobacter pylori in stool of HIV- positive patients
Keywords:
Helicobacter pylori, HIV, flagellar sheath adhesin, (hpaA), urea amidohydrolase (ureB), gastric.Abstract
Helicobacter Pylori is a bacillus that naturally colonizes humans, living in gastric mucus. Association of
H. pylori colonization of stomach with chronic gastritis, peptic ulcer and gastric malignancies has been
well documented. In this study, we aimed to find presence of H. pylori in stool of HIV infected patients
by PCR. 43 patients who had confirmed HIV-infection were subjected. Specific primers for hpaA
(flagellar sheath adhesin) and ureB (urea amidohydrolase), of H. pylori were designed and, presence of
the genome of H. pylori investigated by PCR method. 35 of the patients (81.39%) had CD4+ count below
200 and H. pylori was found in 30 patients (69.76%). Results show from screening by H. pylori in stool
of HIV-infected patients that prevalence of this bacterium in these patients is high. This prevalence is
similar to prevalence of H. pylori in HIV-non infected population.
